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Entorhinal Cortex dysfunction can be rescued by inhibition of microglial RAGE in an Alzheimer’s disease mouse model

The Entorhinal cortex (EC) has been implicated in the early stages of Alzheimer’s disease (AD). In particular, spreading of neuronal dysfunction within the EC-Hippocampal network has been suggested. We have investigated the time course of EC dysfunction in the AD mouse model carrying human mutation...

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Detalles Bibliográficos
Autores principales: Criscuolo, Chiara, Fontebasso, Veronica, Middei, Silvia, Stazi, Martina, Ammassari-Teule, Martine, Yan, Shirley ShiDu, Origlia, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304222/
https://www.ncbi.nlm.nih.gov/pubmed/28205565
http://dx.doi.org/10.1038/srep42370

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