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Entorhinal Cortex dysfunction can be rescued by inhibition of microglial RAGE in an Alzheimer’s disease mouse model
The Entorhinal cortex (EC) has been implicated in the early stages of Alzheimer’s disease (AD). In particular, spreading of neuronal dysfunction within the EC-Hippocampal network has been suggested. We have investigated the time course of EC dysfunction in the AD mouse model carrying human mutation...
Autores principales: | Criscuolo, Chiara, Fontebasso, Veronica, Middei, Silvia, Stazi, Martina, Ammassari-Teule, Martine, Yan, Shirley ShiDu, Origlia, Nicola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304222/ https://www.ncbi.nlm.nih.gov/pubmed/28205565 http://dx.doi.org/10.1038/srep42370 |
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