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Inhibition of TNF Receptor p55 By a Domain Antibody Attenuates the Initial Phase of Acid-Induced Lung Injury in Mice

BACKGROUND: Tumor necrosis factor-α (TNF) is strongly implicated in the development of acute respiratory distress syndrome (ARDS), but its potential as a therapeutic target has been hampered by its complex biology. TNF signals through two receptors, p55 and p75, which play differential roles in pulm...

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Detalles Bibliográficos
Autores principales:	Wilson, Michael R., Wakabayashi, Kenji, Bertok, Szabolcs, Oakley, Charlotte M., Patel, Brijesh V., O’Dea, Kieran P., Cordy, Joanna C., Morley, Peter J., Bayliffe, Andrew I., Takata, Masao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304467/ https://www.ncbi.nlm.nih.gov/pubmed/28243236 http://dx.doi.org/10.3389/fimmu.2017.00128

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