Estimating vaccine effectiveness in preventing laboratory‐confirmed influenza in outpatient settings in South Africa, 2015

Trivalent seasonal influenza vaccine effectiveness during the 2015 season in South Africa was assessed using a test‐negative case control study design. Influenza A(H1N1)pdm09 was the dominant circulating strain. Overall influenza vaccine coverage was 3.2% (29/899). The vaccine effectiveness estimate...

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Detalles Bibliográficos
Autores principales: McAnerney, Johanna M., Walaza, Sibongile, Tempia, Stefano, Blumberg, Lucille, Treurnicht, Florette K., Madhi, Shabir A., Valley‐Omar, Ziyaad, Cohen, Cheryl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304569/
https://www.ncbi.nlm.nih.gov/pubmed/27865064
http://dx.doi.org/10.1111/irv.12436
Descripción
Sumario:Trivalent seasonal influenza vaccine effectiveness during the 2015 season in South Africa was assessed using a test‐negative case control study design. Influenza A(H1N1)pdm09 was the dominant circulating strain. Overall influenza vaccine coverage was 3.2% (29/899). The vaccine effectiveness estimate, against any influenza virus infection, adjusted for age, underlying conditions and timing within season was 46.2% (95% CI: −23.5 to 76.5), and 53.6% (95% CI: −62.6 to 80.3) against influenza A(H1N1)pdm09.

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