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Estimating vaccine effectiveness in preventing laboratory‐confirmed influenza in outpatient settings in South Africa, 2015

Trivalent seasonal influenza vaccine effectiveness during the 2015 season in South Africa was assessed using a test‐negative case control study design. Influenza A(H1N1)pdm09 was the dominant circulating strain. Overall influenza vaccine coverage was 3.2% (29/899). The vaccine effectiveness estimate...

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Autores principales: McAnerney, Johanna M., Walaza, Sibongile, Tempia, Stefano, Blumberg, Lucille, Treurnicht, Florette K., Madhi, Shabir A., Valley‐Omar, Ziyaad, Cohen, Cheryl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304569/
https://www.ncbi.nlm.nih.gov/pubmed/27865064
http://dx.doi.org/10.1111/irv.12436
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author McAnerney, Johanna M.
Walaza, Sibongile
Tempia, Stefano
Blumberg, Lucille
Treurnicht, Florette K.
Madhi, Shabir A.
Valley‐Omar, Ziyaad
Cohen, Cheryl
author_facet McAnerney, Johanna M.
Walaza, Sibongile
Tempia, Stefano
Blumberg, Lucille
Treurnicht, Florette K.
Madhi, Shabir A.
Valley‐Omar, Ziyaad
Cohen, Cheryl
author_sort McAnerney, Johanna M.
collection PubMed
description Trivalent seasonal influenza vaccine effectiveness during the 2015 season in South Africa was assessed using a test‐negative case control study design. Influenza A(H1N1)pdm09 was the dominant circulating strain. Overall influenza vaccine coverage was 3.2% (29/899). The vaccine effectiveness estimate, against any influenza virus infection, adjusted for age, underlying conditions and timing within season was 46.2% (95% CI: −23.5 to 76.5), and 53.6% (95% CI: −62.6 to 80.3) against influenza A(H1N1)pdm09.
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spelling pubmed-53045692017-03-17 Estimating vaccine effectiveness in preventing laboratory‐confirmed influenza in outpatient settings in South Africa, 2015 McAnerney, Johanna M. Walaza, Sibongile Tempia, Stefano Blumberg, Lucille Treurnicht, Florette K. Madhi, Shabir A. Valley‐Omar, Ziyaad Cohen, Cheryl Influenza Other Respir Viruses Short Report Trivalent seasonal influenza vaccine effectiveness during the 2015 season in South Africa was assessed using a test‐negative case control study design. Influenza A(H1N1)pdm09 was the dominant circulating strain. Overall influenza vaccine coverage was 3.2% (29/899). The vaccine effectiveness estimate, against any influenza virus infection, adjusted for age, underlying conditions and timing within season was 46.2% (95% CI: −23.5 to 76.5), and 53.6% (95% CI: −62.6 to 80.3) against influenza A(H1N1)pdm09. John Wiley and Sons Inc. 2016-12-20 2017-03 /pmc/articles/PMC5304569/ /pubmed/27865064 http://dx.doi.org/10.1111/irv.12436 Text en © 2016 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Report
McAnerney, Johanna M.
Walaza, Sibongile
Tempia, Stefano
Blumberg, Lucille
Treurnicht, Florette K.
Madhi, Shabir A.
Valley‐Omar, Ziyaad
Cohen, Cheryl
Estimating vaccine effectiveness in preventing laboratory‐confirmed influenza in outpatient settings in South Africa, 2015
title Estimating vaccine effectiveness in preventing laboratory‐confirmed influenza in outpatient settings in South Africa, 2015
title_full Estimating vaccine effectiveness in preventing laboratory‐confirmed influenza in outpatient settings in South Africa, 2015
title_fullStr Estimating vaccine effectiveness in preventing laboratory‐confirmed influenza in outpatient settings in South Africa, 2015
title_full_unstemmed Estimating vaccine effectiveness in preventing laboratory‐confirmed influenza in outpatient settings in South Africa, 2015
title_short Estimating vaccine effectiveness in preventing laboratory‐confirmed influenza in outpatient settings in South Africa, 2015
title_sort estimating vaccine effectiveness in preventing laboratory‐confirmed influenza in outpatient settings in south africa, 2015
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304569/
https://www.ncbi.nlm.nih.gov/pubmed/27865064
http://dx.doi.org/10.1111/irv.12436
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