Cargando…
Multifunctional Nanomaterials and Their Applications in Drug Delivery and Cancer Therapy
The field of nanotechnology has led to the development of many innovative strategies for effective detection and treatment of cancer, overcoming limitations associated with conventional cancer diagnosis and therapy. Multifunctional nanoparticle systems can integrate imaging, targeting and treatment...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304767/ https://www.ncbi.nlm.nih.gov/pubmed/28347089 http://dx.doi.org/10.3390/nano5041690 |
_version_ | 1782506942096211968 |
---|---|
author | Srinivasan, Mathangi Rajabi, Mehdi Mousa, Shaker A. |
author_facet | Srinivasan, Mathangi Rajabi, Mehdi Mousa, Shaker A. |
author_sort | Srinivasan, Mathangi |
collection | PubMed |
description | The field of nanotechnology has led to the development of many innovative strategies for effective detection and treatment of cancer, overcoming limitations associated with conventional cancer diagnosis and therapy. Multifunctional nanoparticle systems can integrate imaging, targeting and treatment moieties on the surface and in the core, resulting in targeted delivery of the imaging or treatment modalities, specifically to the tumor. Multifunctional nanoparticles also enable simultaneous delivery of multiple treatment agents, resulting in effective combinatorial therapeutic regimens against cancer. In this review, various multifunctional nanoparticle systems that feature a variety of targeting moieties for in vitro and/or in vivo cancer imaging and therapy are discussed. |
format | Online Article Text |
id | pubmed-5304767 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-53047672017-03-21 Multifunctional Nanomaterials and Their Applications in Drug Delivery and Cancer Therapy Srinivasan, Mathangi Rajabi, Mehdi Mousa, Shaker A. Nanomaterials (Basel) Review The field of nanotechnology has led to the development of many innovative strategies for effective detection and treatment of cancer, overcoming limitations associated with conventional cancer diagnosis and therapy. Multifunctional nanoparticle systems can integrate imaging, targeting and treatment moieties on the surface and in the core, resulting in targeted delivery of the imaging or treatment modalities, specifically to the tumor. Multifunctional nanoparticles also enable simultaneous delivery of multiple treatment agents, resulting in effective combinatorial therapeutic regimens against cancer. In this review, various multifunctional nanoparticle systems that feature a variety of targeting moieties for in vitro and/or in vivo cancer imaging and therapy are discussed. MDPI 2015-10-14 /pmc/articles/PMC5304767/ /pubmed/28347089 http://dx.doi.org/10.3390/nano5041690 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Srinivasan, Mathangi Rajabi, Mehdi Mousa, Shaker A. Multifunctional Nanomaterials and Their Applications in Drug Delivery and Cancer Therapy |
title | Multifunctional Nanomaterials and Their Applications in Drug Delivery and Cancer Therapy |
title_full | Multifunctional Nanomaterials and Their Applications in Drug Delivery and Cancer Therapy |
title_fullStr | Multifunctional Nanomaterials and Their Applications in Drug Delivery and Cancer Therapy |
title_full_unstemmed | Multifunctional Nanomaterials and Their Applications in Drug Delivery and Cancer Therapy |
title_short | Multifunctional Nanomaterials and Their Applications in Drug Delivery and Cancer Therapy |
title_sort | multifunctional nanomaterials and their applications in drug delivery and cancer therapy |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304767/ https://www.ncbi.nlm.nih.gov/pubmed/28347089 http://dx.doi.org/10.3390/nano5041690 |
work_keys_str_mv | AT srinivasanmathangi multifunctionalnanomaterialsandtheirapplicationsindrugdeliveryandcancertherapy AT rajabimehdi multifunctionalnanomaterialsandtheirapplicationsindrugdeliveryandcancertherapy AT mousashakera multifunctionalnanomaterialsandtheirapplicationsindrugdeliveryandcancertherapy |