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Multifunctional Nanomaterials and Their Applications in Drug Delivery and Cancer Therapy

The field of nanotechnology has led to the development of many innovative strategies for effective detection and treatment of cancer, overcoming limitations associated with conventional cancer diagnosis and therapy. Multifunctional nanoparticle systems can integrate imaging, targeting and treatment...

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Detalles Bibliográficos
Autores principales: Srinivasan, Mathangi, Rajabi, Mehdi, Mousa, Shaker A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304767/
https://www.ncbi.nlm.nih.gov/pubmed/28347089
http://dx.doi.org/10.3390/nano5041690
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author Srinivasan, Mathangi
Rajabi, Mehdi
Mousa, Shaker A.
author_facet Srinivasan, Mathangi
Rajabi, Mehdi
Mousa, Shaker A.
author_sort Srinivasan, Mathangi
collection PubMed
description The field of nanotechnology has led to the development of many innovative strategies for effective detection and treatment of cancer, overcoming limitations associated with conventional cancer diagnosis and therapy. Multifunctional nanoparticle systems can integrate imaging, targeting and treatment moieties on the surface and in the core, resulting in targeted delivery of the imaging or treatment modalities, specifically to the tumor. Multifunctional nanoparticles also enable simultaneous delivery of multiple treatment agents, resulting in effective combinatorial therapeutic regimens against cancer. In this review, various multifunctional nanoparticle systems that feature a variety of targeting moieties for in vitro and/or in vivo cancer imaging and therapy are discussed.
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spelling pubmed-53047672017-03-21 Multifunctional Nanomaterials and Their Applications in Drug Delivery and Cancer Therapy Srinivasan, Mathangi Rajabi, Mehdi Mousa, Shaker A. Nanomaterials (Basel) Review The field of nanotechnology has led to the development of many innovative strategies for effective detection and treatment of cancer, overcoming limitations associated with conventional cancer diagnosis and therapy. Multifunctional nanoparticle systems can integrate imaging, targeting and treatment moieties on the surface and in the core, resulting in targeted delivery of the imaging or treatment modalities, specifically to the tumor. Multifunctional nanoparticles also enable simultaneous delivery of multiple treatment agents, resulting in effective combinatorial therapeutic regimens against cancer. In this review, various multifunctional nanoparticle systems that feature a variety of targeting moieties for in vitro and/or in vivo cancer imaging and therapy are discussed. MDPI 2015-10-14 /pmc/articles/PMC5304767/ /pubmed/28347089 http://dx.doi.org/10.3390/nano5041690 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Srinivasan, Mathangi
Rajabi, Mehdi
Mousa, Shaker A.
Multifunctional Nanomaterials and Their Applications in Drug Delivery and Cancer Therapy
title Multifunctional Nanomaterials and Their Applications in Drug Delivery and Cancer Therapy
title_full Multifunctional Nanomaterials and Their Applications in Drug Delivery and Cancer Therapy
title_fullStr Multifunctional Nanomaterials and Their Applications in Drug Delivery and Cancer Therapy
title_full_unstemmed Multifunctional Nanomaterials and Their Applications in Drug Delivery and Cancer Therapy
title_short Multifunctional Nanomaterials and Their Applications in Drug Delivery and Cancer Therapy
title_sort multifunctional nanomaterials and their applications in drug delivery and cancer therapy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304767/
https://www.ncbi.nlm.nih.gov/pubmed/28347089
http://dx.doi.org/10.3390/nano5041690
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