Nanocarriers for DNA Vaccines: Co-Delivery of TLR-9 and NLR-2 Ligands Leads to Synergistic Enhancement of Proinflammatory Cytokine Release

Adjuvants enhance immunogenicity of vaccines through either targeted antigen delivery or stimulation of immune receptors. Three cationic nanoparticle formulations were evaluated for their potential as carriers for a DNA vaccine, and muramyl dipeptide (MDP) as immunostimulatory agent, to induce and i...

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Detalles Bibliográficos
Autores principales: Poecheim, Johanna, Heuking, Simon, Brunner, Livia, Barnier-Quer, Christophe, Collin, Nicolas, Borchard, Gerrit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304807/
https://www.ncbi.nlm.nih.gov/pubmed/28347123
http://dx.doi.org/10.3390/nano5042317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304807/
https://www.ncbi.nlm.nih.gov/pubmed/28347123
http://dx.doi.org/10.3390/nano5042317

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