Insights into Pyrazinamidase and DNA Gyrase Protein Structures in Resistant and Susceptible Clinical Isolates of Mycobacterium tuberculosis

BACKGROUND: Mutations in pncA and gyrA genes cause pyrazinamide (PZA) and fluroquinolone resistance in Mycobacterium tuberculosis (MTB). In the present study, structures of pyrazinamidase (PZase) and DNA gyrase proteins were studied in resistant and susceptible clinical isolates of MTB. MATERIALS AN...

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Detalles Bibliográficos
Autores principales: Ahmadi, Azam, Nazari, Raziyeh, Arjomandzadegan, Mohammad, Zolfaghari, Mohammad Reza, Vahidi, Vahideh, Poolad, Toktam, Kahbazi, Manijeh, Sadrnia, Maryam, Tousheh, Mojtaba, Rafiee, Pourya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Research Institute of Tuberculosis and Lung Disease 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304958/
https://www.ncbi.nlm.nih.gov/pubmed/28210279

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