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Bile salt receptor TGR5 is highly expressed in esophageal adenocarcinoma and precancerous lesions with significantly worse overall survival and gender differences

Bile acid reflux in the esophagus plays an important role in the carcinogenesis of esophageal adenocarcinoma (EAC). The G-protein coupled bile acid receptor (TGR5) has been associated with the development of gastrointestinal cancer. However, little is known regarding the role of TGR5 in esophageal c...

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Detalles Bibliográficos
Autores principales: Pang, Chunhong, LaLonde, Amy, Godfrey, Tony E, Que, Jianwen, Sun, Jun, Wu, Tong Tong, Zhou, Zhongren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5304980/
https://www.ncbi.nlm.nih.gov/pubmed/28223834
http://dx.doi.org/10.2147/CEG.S117842