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Mapping the methylation status of the miR-145 promoter in saphenous vein smooth muscle cells from individuals with type 2 diabetes
Type 2 diabetes mellitus prevalence is growing globally, and the leading cause of mortality in these patients is cardiovascular disease. Epigenetic mechanisms such as microRNAs (miRs) and DNA methylation may contribute to complications of type 2 diabetes mellitus. We discovered an aberrant type 2 di...
Autores principales: | Riches, Kirsten, Huntriss, John, Keeble, Claire, Wood, Ian C, O’Regan, David J, Turner, Neil A, Porter, Karen E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305035/ https://www.ncbi.nlm.nih.gov/pubmed/28185533 http://dx.doi.org/10.1177/1479164116677968 |
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