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Mapping the methylation status of the miR-145 promoter in saphenous vein smooth muscle cells from individuals with type 2 diabetes

Type 2 diabetes mellitus prevalence is growing globally, and the leading cause of mortality in these patients is cardiovascular disease. Epigenetic mechanisms such as microRNAs (miRs) and DNA methylation may contribute to complications of type 2 diabetes mellitus. We discovered an aberrant type 2 di...

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Detalles Bibliográficos
Autores principales: Riches, Kirsten, Huntriss, John, Keeble, Claire, Wood, Ian C, O’Regan, David J, Turner, Neil A, Porter, Karen E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305035/
https://www.ncbi.nlm.nih.gov/pubmed/28185533
http://dx.doi.org/10.1177/1479164116677968

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