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Patterns of clinical nail appearances in patients with cutaneous psoriasis

BACKGROUND AND AIM: Nail manifestations are often an overlooked aspect in psoriatic disease, cutaneous and joint involvement being far more often reported and investigated. The reported prevalence of nail changes varies in literature, specific fingernail clinical features having different degrees of...

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Autores principales: MARINA, ELENA MIHAELA, BOTAR-JID, CAROLINA, BOLBOACA, SORANA DANIELA, ROMAN, IULIA IOANA, SENILA, CORINA SIMONA, MIHU, CARMEN MIHAELA, TATARU, DUMITRU ALEXANDRU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iuliu Hatieganu University of Medicine and Pharmacy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305083/
https://www.ncbi.nlm.nih.gov/pubmed/28246493
http://dx.doi.org/10.15386/cjmed-679
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author MARINA, ELENA MIHAELA
BOTAR-JID, CAROLINA
BOLBOACA, SORANA DANIELA
ROMAN, IULIA IOANA
SENILA, CORINA SIMONA
MIHU, CARMEN MIHAELA
TATARU, DUMITRU ALEXANDRU
author_facet MARINA, ELENA MIHAELA
BOTAR-JID, CAROLINA
BOLBOACA, SORANA DANIELA
ROMAN, IULIA IOANA
SENILA, CORINA SIMONA
MIHU, CARMEN MIHAELA
TATARU, DUMITRU ALEXANDRU
author_sort MARINA, ELENA MIHAELA
collection PubMed
description BACKGROUND AND AIM: Nail manifestations are often an overlooked aspect in psoriatic disease, cutaneous and joint involvement being far more often reported and investigated. The reported prevalence of nail changes varies in literature, specific fingernail clinical features having different degrees of occurrence. The aim of this study was to describe specific clinical patterns of fingernail alterations in adult patients with plaque-type psoriasis in a university hospital in the North-West of Romania. METHODS: Clinical data of 35 patients with fingernail psoriasis were collected and analyzed. Psoriasis Area and Severity Index (PASI) and Nail Psoriasis Severity Index (NAPSI) scores were used to quantify disease extension in each patient. RESULTS: PASI score proved linearly correlated with NAPSI score (p<0.05). The age of onset of fingernail psoriasis was positively correlated with age of onset cutaneous psoriasis (p<0.0001). Furthermore, the duration of cutaneous involvement and NAPSI proved significantly related (p<0.05). The third fingernail in the right hand and first fingernail in the left hand were in most of the cases severely affected. The most common observed nail pattern was pitting, followed by salmon patches and subungual hyperkeratosis. CONCLUSION: Important nail changes appear even in moderate forms of cutaneous psoriasis. Particular localization of specific fingernail psoriasis pattern enables the possibility of detecting early stage disease.
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spelling pubmed-53050832017-02-28 Patterns of clinical nail appearances in patients with cutaneous psoriasis MARINA, ELENA MIHAELA BOTAR-JID, CAROLINA BOLBOACA, SORANA DANIELA ROMAN, IULIA IOANA SENILA, CORINA SIMONA MIHU, CARMEN MIHAELA TATARU, DUMITRU ALEXANDRU Clujul Med Original Research BACKGROUND AND AIM: Nail manifestations are often an overlooked aspect in psoriatic disease, cutaneous and joint involvement being far more often reported and investigated. The reported prevalence of nail changes varies in literature, specific fingernail clinical features having different degrees of occurrence. The aim of this study was to describe specific clinical patterns of fingernail alterations in adult patients with plaque-type psoriasis in a university hospital in the North-West of Romania. METHODS: Clinical data of 35 patients with fingernail psoriasis were collected and analyzed. Psoriasis Area and Severity Index (PASI) and Nail Psoriasis Severity Index (NAPSI) scores were used to quantify disease extension in each patient. RESULTS: PASI score proved linearly correlated with NAPSI score (p<0.05). The age of onset of fingernail psoriasis was positively correlated with age of onset cutaneous psoriasis (p<0.0001). Furthermore, the duration of cutaneous involvement and NAPSI proved significantly related (p<0.05). The third fingernail in the right hand and first fingernail in the left hand were in most of the cases severely affected. The most common observed nail pattern was pitting, followed by salmon patches and subungual hyperkeratosis. CONCLUSION: Important nail changes appear even in moderate forms of cutaneous psoriasis. Particular localization of specific fingernail psoriasis pattern enables the possibility of detecting early stage disease. Iuliu Hatieganu University of Medicine and Pharmacy 2017 2017-01-15 /pmc/articles/PMC5305083/ /pubmed/28246493 http://dx.doi.org/10.15386/cjmed-679 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
spellingShingle Original Research
MARINA, ELENA MIHAELA
BOTAR-JID, CAROLINA
BOLBOACA, SORANA DANIELA
ROMAN, IULIA IOANA
SENILA, CORINA SIMONA
MIHU, CARMEN MIHAELA
TATARU, DUMITRU ALEXANDRU
Patterns of clinical nail appearances in patients with cutaneous psoriasis
title Patterns of clinical nail appearances in patients with cutaneous psoriasis
title_full Patterns of clinical nail appearances in patients with cutaneous psoriasis
title_fullStr Patterns of clinical nail appearances in patients with cutaneous psoriasis
title_full_unstemmed Patterns of clinical nail appearances in patients with cutaneous psoriasis
title_short Patterns of clinical nail appearances in patients with cutaneous psoriasis
title_sort patterns of clinical nail appearances in patients with cutaneous psoriasis
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305083/
https://www.ncbi.nlm.nih.gov/pubmed/28246493
http://dx.doi.org/10.15386/cjmed-679
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