Acquired resistance to oxaliplatin is not directly associated with increased resistance to DNA damage in SK-N-AS(r)OXALI(4000), a newly established oxaliplatin-resistant sub-line of the neuroblastoma cell line SK-N-AS

The formation of acquired drug resistance is a major reason for the failure of anti-cancer therapies after initial response. Here, we introduce a novel model of acquired oxaliplatin resistance, a sub-line of the non-MYCN-amplified neuroblastoma cell line SK-N-AS that was adapted to growth in the pre...

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Detalles Bibliográficos
Autores principales: Saintas, Emily, Abrahams, Liam, Ahmad, Gulshan T., Ajakaiye, Anu-Oluwa M., AlHumaidi, Abdulaziz S. H. A. M., Ashmore-Harris, Candice, Clark, Iain, Dura, Usha K., Fixmer, Carine N., Ike-Morris, Chinedu, Mato Prado, Mireia, Mccullough, Danielle, Mishra, Shishir, Schöler, Katia M. U., Timur, Husne, Williamson, Maxwell D. C., Alatsatianos, Markella, Bahsoun, Basma, Blackburn, Edith, Hogwood, Catherine E., Lithgow, Pamela E., Rowe, Michelle, Yiangou, Lyto, Rothweiler, Florian, Cinatl, Jindrich, Zehner, Richard, Baines, Anthony J., Garrett, Michelle D., Gourlay, Campbell W., Griffin, Darren K., Gullick, William J., Hargreaves, Emma, Howard, Mark J., Lloyd, Daniel R., Rossman, Jeremy S., Smales, C. Mark, Tsaousis, Anastasios D., von der Haar, Tobias, Wass, Mark N., Michaelis, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305101/
https://www.ncbi.nlm.nih.gov/pubmed/28192521
http://dx.doi.org/10.1371/journal.pone.0172140

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