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Gene regulatory effects of disease-associated variation in the NRF2 network
Reactive oxygen species (ROS), which are both a natural byproduct of oxidative metabolism and an undesirable byproduct of many environmental stressors, can damage all classes of cellular macromolecules and promote diseases from cancer to neurodegeneration. The actions of ROS are mitigated by the tra...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305174/ https://www.ncbi.nlm.nih.gov/pubmed/28203648 http://dx.doi.org/10.1016/j.cotox.2016.09.001 |