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Selective expansion of high functional avidity memory CD8 T cell clonotypes during hepatitis C virus reinfection and clearance

The dynamics of the memory CD8 T cell receptor (TCR) repertoire upon virus re-exposure and factors governing the selection of TCR clonotypes conferring protective immunity in real life settings are poorly understood. Here, we examined the dynamics and functionality of the virus-specific memory CD8 T...

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Detalles Bibliográficos
Autores principales:	Abdel-Hakeem, Mohamed S., Boisvert, Maude, Bruneau, Julie, Soudeyns, Hugo, Shoukry, Naglaa H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305272/ https://www.ncbi.nlm.nih.gov/pubmed/28146579 http://dx.doi.org/10.1371/journal.ppat.1006191

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