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Brief Report: Decentralizing ART Supply for Stable HIV Patients to Community-Based Distribution Centers: Program Outcomes From an Urban Context in Kinshasa, DRC

Facility-based antiretroviral therapy (ART) provision for stable patients with HIV congests health services in resource-limited countries. We assessed outcomes and risk factors for attrition after decentralization to community-based ART refill centers among 2603 patients with HIV in Kinshasa, Democr...

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Autores principales: Vogt, Florian, Kalenga, Lucien, Lukela, Jean, Salumu, Freddy, Diallo, Ibrahim, Nico, Elena, Lampart, Emmanuel, Van den Bergh, Rafael, Shah, Safieh, Ogundahunsi, Olumide, Zachariah, Rony, Van Griensven, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAIDS Journal of Acquired Immune Deficiency Syndromes 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305289/
https://www.ncbi.nlm.nih.gov/pubmed/27787343
http://dx.doi.org/10.1097/QAI.0000000000001215
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author Vogt, Florian
Kalenga, Lucien
Lukela, Jean
Salumu, Freddy
Diallo, Ibrahim
Nico, Elena
Lampart, Emmanuel
Van den Bergh, Rafael
Shah, Safieh
Ogundahunsi, Olumide
Zachariah, Rony
Van Griensven, Johan
author_facet Vogt, Florian
Kalenga, Lucien
Lukela, Jean
Salumu, Freddy
Diallo, Ibrahim
Nico, Elena
Lampart, Emmanuel
Van den Bergh, Rafael
Shah, Safieh
Ogundahunsi, Olumide
Zachariah, Rony
Van Griensven, Johan
author_sort Vogt, Florian
collection PubMed
description Facility-based antiretroviral therapy (ART) provision for stable patients with HIV congests health services in resource-limited countries. We assessed outcomes and risk factors for attrition after decentralization to community-based ART refill centers among 2603 patients with HIV in Kinshasa, Democratic Republic of Congo, using a multilevel Poisson regression model. Death, loss to follow-up, and transfer out were 0.3%, 9.0%, and 0.7%, respectively, at 24 months. Overall attrition was 5.66/100 person-years. Patients with >3 years on ART, >500 cluster of differentiation type-4 count, body mass index >18.5, and receiving nevirapine but not stavudine showed reduced attrition. ART refill centers are a promising task-shifting model in low-prevalence urban settings with high levels of stigma and poor ART coverage.
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spelling pubmed-53052892017-02-21 Brief Report: Decentralizing ART Supply for Stable HIV Patients to Community-Based Distribution Centers: Program Outcomes From an Urban Context in Kinshasa, DRC Vogt, Florian Kalenga, Lucien Lukela, Jean Salumu, Freddy Diallo, Ibrahim Nico, Elena Lampart, Emmanuel Van den Bergh, Rafael Shah, Safieh Ogundahunsi, Olumide Zachariah, Rony Van Griensven, Johan J Acquir Immune Defic Syndr Clinical Science Facility-based antiretroviral therapy (ART) provision for stable patients with HIV congests health services in resource-limited countries. We assessed outcomes and risk factors for attrition after decentralization to community-based ART refill centers among 2603 patients with HIV in Kinshasa, Democratic Republic of Congo, using a multilevel Poisson regression model. Death, loss to follow-up, and transfer out were 0.3%, 9.0%, and 0.7%, respectively, at 24 months. Overall attrition was 5.66/100 person-years. Patients with >3 years on ART, >500 cluster of differentiation type-4 count, body mass index >18.5, and receiving nevirapine but not stavudine showed reduced attrition. ART refill centers are a promising task-shifting model in low-prevalence urban settings with high levels of stigma and poor ART coverage. JAIDS Journal of Acquired Immune Deficiency Syndromes 2017-03-01 2017-02-14 /pmc/articles/PMC5305289/ /pubmed/27787343 http://dx.doi.org/10.1097/QAI.0000000000001215 Text en Copyright © 2016 The Author(s). Published by Wolters Kluwer Health, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Clinical Science
Vogt, Florian
Kalenga, Lucien
Lukela, Jean
Salumu, Freddy
Diallo, Ibrahim
Nico, Elena
Lampart, Emmanuel
Van den Bergh, Rafael
Shah, Safieh
Ogundahunsi, Olumide
Zachariah, Rony
Van Griensven, Johan
Brief Report: Decentralizing ART Supply for Stable HIV Patients to Community-Based Distribution Centers: Program Outcomes From an Urban Context in Kinshasa, DRC
title Brief Report: Decentralizing ART Supply for Stable HIV Patients to Community-Based Distribution Centers: Program Outcomes From an Urban Context in Kinshasa, DRC
title_full Brief Report: Decentralizing ART Supply for Stable HIV Patients to Community-Based Distribution Centers: Program Outcomes From an Urban Context in Kinshasa, DRC
title_fullStr Brief Report: Decentralizing ART Supply for Stable HIV Patients to Community-Based Distribution Centers: Program Outcomes From an Urban Context in Kinshasa, DRC
title_full_unstemmed Brief Report: Decentralizing ART Supply for Stable HIV Patients to Community-Based Distribution Centers: Program Outcomes From an Urban Context in Kinshasa, DRC
title_short Brief Report: Decentralizing ART Supply for Stable HIV Patients to Community-Based Distribution Centers: Program Outcomes From an Urban Context in Kinshasa, DRC
title_sort brief report: decentralizing art supply for stable hiv patients to community-based distribution centers: program outcomes from an urban context in kinshasa, drc
topic Clinical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305289/
https://www.ncbi.nlm.nih.gov/pubmed/27787343
http://dx.doi.org/10.1097/QAI.0000000000001215
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