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Physiologically based kinetic modeling of the bioactivation of myristicin
The present study describes physiologically based kinetic (PBK) models for the alkenylbenzene myristicin that were developed by extension of the PBK models for the structurally related alkenylbenzene safrole in rat and human. The newly developed myristicin models revealed that the formation of the p...
Autores principales: | Al-Malahmeh, Amer J., Al-Ajlouni, Abdelmajeed, Wesseling, Sebastiaan, Soffers, Ans E. M. F., Al-Subeihi, Ala’, Kiwamoto, Reiko, Vervoort, Jacques, Rietjens, Ivonne M. C. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306082/ https://www.ncbi.nlm.nih.gov/pubmed/27334372 http://dx.doi.org/10.1007/s00204-016-1752-5 |
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