Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Tox(ukn) and STOP-Tox(ukk) tests

Stem cell-based in vitro test systems can recapitulate specific phases of human development. In the UKK test system, human pluripotent stem cells (hPSCs) randomly differentiate into cells of the three germ layers and their derivatives. In the UKN1 test system, hPSCs differentiate into early neural p...

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Detalles Bibliográficos
Autores principales: Shinde, Vaibhav, Hoelting, Lisa, Srinivasan, Sureshkumar Perumal, Meisig, Johannes, Meganathan, Kesavan, Jagtap, Smita, Grinberg, Marianna, Liebing, Julia, Bluethgen, Nils, Rahnenführer, Jörg, Rempel, Eugen, Stoeber, Regina, Schildknecht, Stefan, Förster, Sunniva, Godoy, Patricio, van Thriel, Christoph, Gaspar, John Antonydas, Hescheler, Jürgen, Waldmann, Tanja, Hengstler, Jan G., Leist, Marcel, Sachinidis, Agapios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
In vitro Systems
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306084/
https://www.ncbi.nlm.nih.gov/pubmed/27188386
http://dx.doi.org/10.1007/s00204-016-1741-8

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