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Lumbar microdiscectomy for sciatica in adolescents: a multicentre observational registry-based study

BACKGROUND: Lumbar disc herniation (LDH) is rare in the adolescent population. Factors predisposing to LDH in adolescents differ from adults with more cases being related to trauma or structural malformations. Further, there are limited data on patient-reported outcomes after lumbar microdiscectomy...

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Autores principales: Gulati, Sasha, Madsbu, Mattis A., Solberg, Tore K., Sørlie, Andreas, Giannadakis, Charalampis, Skram, Marius K., Nygaard, Øystein P., Jakola, Asgeir S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306165/
https://www.ncbi.nlm.nih.gov/pubmed/28091818
http://dx.doi.org/10.1007/s00701-017-3077-4
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author Gulati, Sasha
Madsbu, Mattis A.
Solberg, Tore K.
Sørlie, Andreas
Giannadakis, Charalampis
Skram, Marius K.
Nygaard, Øystein P.
Jakola, Asgeir S.
author_facet Gulati, Sasha
Madsbu, Mattis A.
Solberg, Tore K.
Sørlie, Andreas
Giannadakis, Charalampis
Skram, Marius K.
Nygaard, Øystein P.
Jakola, Asgeir S.
author_sort Gulati, Sasha
collection PubMed
description BACKGROUND: Lumbar disc herniation (LDH) is rare in the adolescent population. Factors predisposing to LDH in adolescents differ from adults with more cases being related to trauma or structural malformations. Further, there are limited data on patient-reported outcomes after lumbar microdiscectomy in adolescents. Our aim was to compare clinical outcomes at 1 year following single-level lumbar microdiscectomy in adolescents (13–19 years old) compared to younger adults (20–50 years old) with LDH. METHODS: Data were collected through the Norwegian Registry for Spine Surgery. Patients were eligible if they had radiculopathy due to LDH, underwent single-level lumbar microdiscectomy between January 2007 and May 2014, and were between 13 and 50 years old at time of surgery. The primary endpoint was change in Oswestry Disability Index (ODI) 1 year after surgery. Secondary endpoints were generic quality of life (EuroQol five dimensions [EQ-5D]), back pain numerical rating scale (NRS), leg pain NRS and complications. RESULTS: A total of 3,245 patients were included (97 patients 13–19 years old and 3,148 patients 20–50 years old). A significant improvement in ODI was observed for the whole population, but there was no difference between groups (0.6; 95% CI, −4.5 to 5.8; p = 0.811). There were no differences between groups concerning EQ-5D (−0.04; 95% CI, −0.15 to 0.07; p = 0.442), back pain NRS (−0.4; 95% CI, −1.2 to 0.4; p = 0.279), leg pain NRS (−0.4; 95% CI, −1.2 to 0.5; p = 0.374) or perioperative complications (1.0% for adolescents, 5.1% for adults, p = 0.072). CONCLUSIONS: The effectiveness and safety of single-level microdiscectomy are similar in adolescents and the adult population at 1-year follow-up.
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spelling pubmed-53061652017-02-24 Lumbar microdiscectomy for sciatica in adolescents: a multicentre observational registry-based study Gulati, Sasha Madsbu, Mattis A. Solberg, Tore K. Sørlie, Andreas Giannadakis, Charalampis Skram, Marius K. Nygaard, Øystein P. Jakola, Asgeir S. Acta Neurochir (Wien) Original Article - Spine BACKGROUND: Lumbar disc herniation (LDH) is rare in the adolescent population. Factors predisposing to LDH in adolescents differ from adults with more cases being related to trauma or structural malformations. Further, there are limited data on patient-reported outcomes after lumbar microdiscectomy in adolescents. Our aim was to compare clinical outcomes at 1 year following single-level lumbar microdiscectomy in adolescents (13–19 years old) compared to younger adults (20–50 years old) with LDH. METHODS: Data were collected through the Norwegian Registry for Spine Surgery. Patients were eligible if they had radiculopathy due to LDH, underwent single-level lumbar microdiscectomy between January 2007 and May 2014, and were between 13 and 50 years old at time of surgery. The primary endpoint was change in Oswestry Disability Index (ODI) 1 year after surgery. Secondary endpoints were generic quality of life (EuroQol five dimensions [EQ-5D]), back pain numerical rating scale (NRS), leg pain NRS and complications. RESULTS: A total of 3,245 patients were included (97 patients 13–19 years old and 3,148 patients 20–50 years old). A significant improvement in ODI was observed for the whole population, but there was no difference between groups (0.6; 95% CI, −4.5 to 5.8; p = 0.811). There were no differences between groups concerning EQ-5D (−0.04; 95% CI, −0.15 to 0.07; p = 0.442), back pain NRS (−0.4; 95% CI, −1.2 to 0.4; p = 0.279), leg pain NRS (−0.4; 95% CI, −1.2 to 0.5; p = 0.374) or perioperative complications (1.0% for adolescents, 5.1% for adults, p = 0.072). CONCLUSIONS: The effectiveness and safety of single-level microdiscectomy are similar in adolescents and the adult population at 1-year follow-up. Springer Vienna 2017-01-16 2017 /pmc/articles/PMC5306165/ /pubmed/28091818 http://dx.doi.org/10.1007/s00701-017-3077-4 Text en © The Author(s) 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article - Spine
Gulati, Sasha
Madsbu, Mattis A.
Solberg, Tore K.
Sørlie, Andreas
Giannadakis, Charalampis
Skram, Marius K.
Nygaard, Øystein P.
Jakola, Asgeir S.
Lumbar microdiscectomy for sciatica in adolescents: a multicentre observational registry-based study
title Lumbar microdiscectomy for sciatica in adolescents: a multicentre observational registry-based study
title_full Lumbar microdiscectomy for sciatica in adolescents: a multicentre observational registry-based study
title_fullStr Lumbar microdiscectomy for sciatica in adolescents: a multicentre observational registry-based study
title_full_unstemmed Lumbar microdiscectomy for sciatica in adolescents: a multicentre observational registry-based study
title_short Lumbar microdiscectomy for sciatica in adolescents: a multicentre observational registry-based study
title_sort lumbar microdiscectomy for sciatica in adolescents: a multicentre observational registry-based study
topic Original Article - Spine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306165/
https://www.ncbi.nlm.nih.gov/pubmed/28091818
http://dx.doi.org/10.1007/s00701-017-3077-4
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