Mouse models of deep vein thrombosis

The pathogenesis of venous thromboembolism (VTE) is still not completely understood. Experimental animals in which human deep vein thrombosis can be modeled are useful tools to investigate the pathogenesis of VTE. Besides the availability of transgenic and genetically modified mice, the use of high...

Descripción completa

Detalles Bibliográficos
Autores principales: Schönfelder, T., Jäckel, S., Wenzel, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Medizin 2016
Materias:
Translationale Forschung
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306225/
https://www.ncbi.nlm.nih.gov/pubmed/28715512
http://dx.doi.org/10.1007/s00772-016-0227-6
_version_ 1782507155794952192
author Schönfelder, T.
Jäckel, S.
Wenzel, P.
author_facet Schönfelder, T.
Jäckel, S.
Wenzel, P.
author_sort Schönfelder, T.
collection PubMed
description The pathogenesis of venous thromboembolism (VTE) is still not completely understood. Experimental animals in which human deep vein thrombosis can be modeled are useful tools to investigate the pathogenesis of VTE. Besides the availability of transgenic and genetically modified mice, the use of high frequency ultrasound and intravital microscopy plays an important role in identifying thrombotic processes in mouse models. In this article, an overview about the application of various new technologies and existing mouse models is provided, and the impact of venous side branches on deep vein thrombosis in the mouse model is discussed.
format Online
Article
Text
id pubmed-5306225
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Springer Medizin
record_format MEDLINE/PubMed
spelling pubmed-53062252017-02-24 Mouse models of deep vein thrombosis Schönfelder, T. Jäckel, S. Wenzel, P. Gefasschirurgie Translationale Forschung The pathogenesis of venous thromboembolism (VTE) is still not completely understood. Experimental animals in which human deep vein thrombosis can be modeled are useful tools to investigate the pathogenesis of VTE. Besides the availability of transgenic and genetically modified mice, the use of high frequency ultrasound and intravital microscopy plays an important role in identifying thrombotic processes in mouse models. In this article, an overview about the application of various new technologies and existing mouse models is provided, and the impact of venous side branches on deep vein thrombosis in the mouse model is discussed. Springer Medizin 2016-12-12 2017 /pmc/articles/PMC5306225/ /pubmed/28715512 http://dx.doi.org/10.1007/s00772-016-0227-6 Text en © The Author(s) 2016 Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Translationale Forschung
Schönfelder, T.
Jäckel, S.
Wenzel, P.
Mouse models of deep vein thrombosis
title Mouse models of deep vein thrombosis
title_full Mouse models of deep vein thrombosis
title_fullStr Mouse models of deep vein thrombosis
title_full_unstemmed Mouse models of deep vein thrombosis
title_short Mouse models of deep vein thrombosis
title_sort mouse models of deep vein thrombosis
topic Translationale Forschung
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306225/
https://www.ncbi.nlm.nih.gov/pubmed/28715512
http://dx.doi.org/10.1007/s00772-016-0227-6
work_keys_str_mv AT schonfeldert mousemodelsofdeepveinthrombosis
AT jackels mousemodelsofdeepveinthrombosis
AT wenzelp mousemodelsofdeepveinthrombosis

Ejemplares similares