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Ocular Drug Distribution After Topical Administration: Population Pharmacokinetic Model in Rabbits
BACKGROUND AND OBJECTIVE: When eye diseases are treated by topical administration, the success of treatment lies in the effective drug concentration in the target tissue. This is why the drug’s pharmacokinetic, in the different substructures of the eye, needs to be explored more accurately during dr...
Autores principales: | Djebli, Nassim, Khier, Sonia, Griguer, Florence, Coutant, Anne-Laure, Tavernier, Alexandra, Fabre, Gerard, Leriche, Caroline, Fabre, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306244/ https://www.ncbi.nlm.nih.gov/pubmed/26820265 http://dx.doi.org/10.1007/s13318-016-0319-4 |
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