Identification of HIF-2α-regulated genes that play a role in human microvascular endothelial sprouting during prolonged hypoxia in vitro

During prolonged hypoxic conditions, endothelial cells change their gene expression to adjust to the low oxygen environment. This process is mainly regulated by the hypoxia-inducible factors, HIF-1α and HIF-2α. Although endothelial cells do not form sprouts during prolonged hypoxic culturing, silenc...

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Detalles Bibliográficos
Autores principales: Nauta, Tessa D., van den Broek, Marloes, Gibbs, Sue, van der Pouw-Kraan, Tineke C. T. M., Oudejans, Cees B., van Hinsbergh, Victor W. M., Koolwijk, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306362/
https://www.ncbi.nlm.nih.gov/pubmed/27699500
http://dx.doi.org/10.1007/s10456-016-9527-4

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