Cargando…

Membrane Active Antimicrobial Peptides: Translating Mechanistic Insights to Design

Antimicrobial peptides (AMPs) are promising next generation antibiotics that hold great potential for combating bacterial resistance. AMPs can be both bacteriostatic and bactericidal, induce rapid killing and display a lower propensity to develop resistance than do conventional antibiotics. Despite...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Jianguo, Koh, Jun-Jie, Liu, Shouping, Lakshminarayanan, Rajamani, Verma, Chandra S., Beuerman, Roger W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306396/ https://www.ncbi.nlm.nih.gov/pubmed/28261050 http://dx.doi.org/10.3389/fnins.2017.00073

Ejemplares similares

Strategies in Translating the Therapeutic Potentials of Host Defense Peptides
por: Ting, Darren Shu Jeng, et al.
Publicado: (2020)

Molecular Insights into the Membrane Affinities of Model Hydrophobes
por: Li, Jianguo, et al.
Publicado: (2018)

Rational Optimization of Conformational Effects Induced By Hydrocarbon Staples in Peptides and their Binding Interfaces
por: Lama, Dilraj, et al.
Publicado: (2013)

Multivalent Antimicrobial Peptides as Therapeutics: Design Principles and Structural Diversities
por: Liu, S. P., et al.
Publicado: (2010)

Evaluation of Host Defense Peptide (CaD23)-Antibiotic Interaction and Mechanism of Action: Insights From Experimental and Molecular Dynamics Simulations Studies
por: Ting, Darren Shu Jeng, et al.
Publicado: (2021)

Synthetic Multivalent Antifungal Peptides Effective against Fungi
por: Lakshminarayanan, Rajamani, et al.
Publicado: (2014)

Host Defense Peptides at the Ocular Surface: Roles in Health and Major Diseases, and Therapeutic Potentials
por: Ting, Darren Shu Jeng, et al.
Publicado: (2022)

Branched Peptide, B2088, Disrupts the Supramolecular Organization of Lipopolysaccharides and Sensitizes the Gram-negative Bacteria
por: Lakshminarayanan, Rajamani, et al.
Publicado: (2016)

Antimicrobial Activity and Cell Selectivity of Synthetic and Biosynthetic Cationic Polymers
por: Venkatesh, Mayandi, et al.
Publicado: (2017)

Burkholderia pseudomallei type III secreted protein BipC: role in actin modulation and translocation activities required for the bacterial intracellular lifecycle
por: Kang, Wen Tyng, et al.
Publicado: (2016)

Defensins knowledgebase: a manually curated database and information source focused on the defensins family of antimicrobial peptides
por: Seebah, Shalin, et al.
Publicado: (2007)

Mechanistic insights into translation inhibition by aminoglycoside antibiotic arbekacin
por: Parajuli, Narayan Prasad, et al.
Publicado: (2021)

Controlling Peptide Function by Directed Assembly Formation: Mechanistic Insights Using Multiscale Modeling on an Antimicrobial Peptide–Drug–Membrane System
por: Kohut, Gergely, et al.
Publicado: (2021)

Inhibition of NLRP3 inflammasome activation by cell-permeable stapled peptides
por: Pal, Arumay, et al.
Publicado: (2019)

Antimicrobial quaternary ammonium organosilane cross-linked nanofibrous collagen scaffolds for tissue engineering
por: Dhand, Chetna, et al.
Publicado: (2018)

Characterizing the Conformational Landscape of Flavivirus Fusion Peptides via Simulation and Experiment
por: Marzinek, Jan K., et al.
Publicado: (2016)

Rational design of transcranial current stimulation (TCS) through mechanistic insights into cortical network dynamics
por: Fröhlich, Flavio, et al.
Publicado: (2013)

Design and evaluation of tadpole-like conformational antimicrobial peptides
por: Tang, Ziyi, et al.
Publicado: (2023)

Mechanistic Insight into the Early Stages of Toroidal Pore Formation by the Antimicrobial Peptide Smp24
por: Bertelsen, Magnus, et al.
Publicado: (2023)

Mitochondrial Dysfunction in Parkinson’s Disease: From Mechanistic Insights to Therapy
por: Gao, Xiao-Yan, et al.
Publicado: (2022)

Mechanistic insights and therapeutic opportunities of antimicrobial chemokines
por: Crawford, Matthew A., et al.
Publicado: (2018)

A Mechanistic End-to-End Concussion Model That Translates Head Kinematics to Neurologic Injury
por: Ng, Laurel J., et al.
Publicado: (2017)

Regenerative Approaches in Huntington’s Disease: From Mechanistic Insights to Therapeutic Protocols
por: Sassone, Jenny, et al.
Publicado: (2018)

Exosomes in Age-Related Cognitive Decline: Mechanistic Insights and Improving Outcomes
por: Duggan, Michael R., et al.
Publicado: (2022)

Mechanistic Insights Into MicroRNA-Induced Neuronal Reprogramming of Human Adult Fibroblasts
por: Lu, Ya-Lin, et al.
Publicado: (2018)

Spinocerebellar Ataxia Type 2: Clinicogenetic Aspects, Mechanistic Insights, and Management Approaches
por: Velázquez-Pérez, Luis C., et al.
Publicado: (2017)

New Mechanistic Insights, Novel Treatment Paradigms, and Clinical Progress in Cerebrovascular Diseases
por: Boltze, Johannes, et al.
Publicado: (2021)

A mechanistic insight into sources of error of visual working memory in multiple sclerosis
por: Motahharynia, Ali, et al.
Publicado: (2023)

Stitched peptides as potential cell permeable inhibitors of oncogenic DAXX protein
por: Jelinska, Clare, et al.
Publicado: (2023)

Mechanistic insights into cAMP-mediated presynaptic potentiation at hippocampal mossy fiber synapses
por: Fukaya, Ryota, et al.
Publicado: (2023)

Mechanistic insights into the rational design of masked antibodies
por: Orozco, Carolina T., et al.
Publicado: (2022)

Mechanistic insight into female predominance in Alzheimer’s disease based on aberrant protein S-nitrosylation of C3
por: Yang, Hongmei, et al.
Publicado: (2022)

Dietary phytochemicals and neuro-inflammaging: from mechanistic insights to translational challenges
por: Davinelli, Sergio, et al.
Publicado: (2016)

Mechanistic Insight into Antimicrobial and Antioxidant Potential of Jasminum Species: A Herbal Approach for Disease Management
por: Balkrishna, Acharya, et al.
Publicado: (2021)

Unfolding of the Amyloid β-Peptide Central Helix: Mechanistic Insights from Molecular Dynamics Simulations
por: Ito, Mika, et al.
Publicado: (2011)

Interaction of gelatin with polyenes modulates antifungal activity and biocompatibility of electrospun fiber mats
por: Lakshminarayanan, Rajamani, et al.
Publicado: (2014)

Mechanistic insights into the role of herpes simplex virus 1 in Alzheimer’s disease
por: Feng, Shu, et al.
Publicado: (2023)

Therapeutic Potential of Marine Peptides in Prostate Cancer: Mechanistic Insights
por: Ahmed, Salman, et al.
Publicado: (2022)

Selective Induction of Intrinsic Apoptosis in Retinoblastoma Cells by Novel Cationic Antimicrobial Dodecapeptides
por: Suresh Babu, Vishnu, et al.
Publicado: (2022)

Thermodynamic Insights into the Characteristics of Unary and Mixture Permeances in Microporous Membranes
por: Krishna, Rajamani
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_bri2grhljcia8ucnp3sgf1ole2