Proteomic Analysis of Post-synaptic Density Fractions from Shank3 Mutant Mice Reveals Brain Region Specific Changes Relevant to Autism Spectrum Disorder

Disruption of the human SHANK3 gene can cause several neuropsychiatric disease entities including Phelan-McDermid syndrome, autism spectrum disorder (ASD), and intellectual disability. Although, a wide array of neurobiological studies strongly supports a major role for SHANK3 in organizing the post-...

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Detalles Bibliográficos
Autores principales: Reim, Dominik, Distler, Ute, Halbedl, Sonja, Verpelli, Chiara, Sala, Carlo, Bockmann, Juergen, Tenzer, Stefan, Boeckers, Tobias M., Schmeisser, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306440/
https://www.ncbi.nlm.nih.gov/pubmed/28261056
http://dx.doi.org/10.3389/fnmol.2017.00026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5306440/
https://www.ncbi.nlm.nih.gov/pubmed/28261056
http://dx.doi.org/10.3389/fnmol.2017.00026

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