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The alternative complement pathway is dysregulated in patients with chronic heart failure

The complement system, an important arm of the innate immune system, is activated in heart failure (HF). We hypothesized that HF patients are characterized by an imbalance of alternative amplification loop components; including properdin and complement factor D and the alternative pathway inhibitor...

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Detalles Bibliográficos
Autores principales: Shahini, Negar, Michelsen, Annika E., Nilsson, Per H., Ekholt, Karin, Gullestad, Lars, Broch, Kaspar, Dahl, Christen P., Aukrust, Pål, Ueland, Thor, Mollnes, Tom Eirik, Yndestad, Arne, Louwe, Mieke C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307342/
https://www.ncbi.nlm.nih.gov/pubmed/28195242
http://dx.doi.org/10.1038/srep42532