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Comparison of immunohistochemistry with PCR for assessment of ER, PR, and Ki-67 and prediction of pathological complete response in breast cancer
BACKGROUND: Proliferation may predict response to neoadjuvant therapy of breast cancer and is commonly assessed by manual scoring of slides stained by immunohistochemistry (IHC) for Ki-67 similar to ER and PgR. This method carries significant intra- and inter-observer variability. Automatic scoring...
Autores principales: | Sinn, Hans-Peter, Schneeweiss, Andreas, Keller, Marius, Schlombs, Kornelia, Laible, Mark, Seitz, Julia, Lakis, Sotirios, Veltrup, Elke, Altevogt, Peter, Eidt, Sebastian, Wirtz, Ralph M., Marmé, Frederik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307758/ https://www.ncbi.nlm.nih.gov/pubmed/28193205 http://dx.doi.org/10.1186/s12885-017-3111-1 |
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