A novel point mutation in RpoB improves osmotolerance and succinic acid production in Escherichia coli

BACKGROUND: Escherichia coli suffer from osmotic stress during succinic acid (SA) production, which reduces the performance of this microbial factory. RESULTS: Here, we report that a point mutation leading to a single amino acid change (D654Y) within the β-subunit of DNA-dependent RNA polymerase (Rp...

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Detalles Bibliográficos
Autores principales: Xiao, Mengyong, Zhu, Xinna, Xu, Hongtao, Tang, Jinlei, Liu, Ru, Bi, Changhao, Fan, Feiyu, Zhang, Xueli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307762/
https://www.ncbi.nlm.nih.gov/pubmed/28193207
http://dx.doi.org/10.1186/s12896-017-0337-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307762/
https://www.ncbi.nlm.nih.gov/pubmed/28193207
http://dx.doi.org/10.1186/s12896-017-0337-6

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