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Anti-tumor effects of a recombinant anti-prostate specific membrane antigen immunotoxin against prostate cancer cells

BACKGROUND: To evaluate anti-prostate cancer effects of a chimeric tumor-targeted killer protein. METHODS: We established a novel fusion gene, immunocasp-3, composed of NH2-terminal leader sequence fused with an anti-prostate-specific membrane antigen (PSMA) antibody (J591), the furin cleavage seque...

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Detalles Bibliográficos
Autores principales:	Meng, Ping, Dong, Qing-chuan, Tan, Guang-guo, Wen, Wei-hong, Wang, He, Zhang, Geng, Wang, Yan-zhu, Jing, Yu-ming, Wang, Chen, Qin, Wei-jun, Yuan, Jian-lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307788/ https://www.ncbi.nlm.nih.gov/pubmed/28193277 http://dx.doi.org/10.1186/s12894-017-0203-9

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