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Rapid eradication of colon carcinoma by Clostridium perfringens Enterotoxin suicidal gene therapy

BACKGROUND: Bacterial toxins have evolved to an effective therapeutic option for cancer therapy. The Clostridium perfringens enterotoxin (CPE) is a pore-forming toxin with selective cytotoxicity. The transmembrane tight junction proteins claudin-3 and -4 are known high affinity CPE receptors. Their...

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Detalles Bibliográficos
Autores principales:	Pahle, Jessica, Menzel, Lutz, Niesler, Nicole, Kobelt, Dennis, Aumann, Jutta, Rivera, Maria, Walther, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307849/ https://www.ncbi.nlm.nih.gov/pubmed/28193196 http://dx.doi.org/10.1186/s12885-017-3123-x

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