Cargando…
A high-throughput expression screening platform to optimize the production of antimicrobial peptides
BACKGROUND: Antimicrobial peptides (AMPs) are promising candidates for the development of novel antibiotics, but it is difficult to produce sufficient quantities for preclinical and clinical studies due to their toxicity towards microbial expression hosts. To avoid laborious trial-and-error testing...
Autores principales: | Schreiber, Christine, Müller, Hagen, Birrenbach, Oliver, Klein, Moritz, Heerd, Doreen, Weidner, Tobias, Salzig, Denise, Czermak, Peter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307881/ https://www.ncbi.nlm.nih.gov/pubmed/28193216 http://dx.doi.org/10.1186/s12934-017-0637-5 |
Ejemplares similares
-
Three-Dimensional Bioreactor Technologies for the Cocultivation of Human Mesenchymal Stem/Stromal Cells and Beta Cells
por: Petry, Florian, et al.
Publicado: (2018) -
Single-cell cloning enables the selection of more productive Drosophila melanogaster S2 cells for recombinant protein expression
por: Zitzmann, Jan, et al.
Publicado: (2018) -
Process intensification for the continuous production of an antimicrobial peptide in stably-transformed Sf-9 insect cells
por: Käßer, Lukas, et al.
Publicado: (2022) -
Dielectric Spectroscopy and Optical Density Measurement for the Online Monitoring and Control of Recombinant Protein Production in Stably Transformed Drosophila melanogaster S2 Cells
por: Zitzmann, Jan, et al.
Publicado: (2018) -
Aeration and Shear Stress Are Critical Process Parameters for the Production of Oncolytic Measles Virus
por: Grein, Tanja A., et al.
Publicado: (2019)