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A high-throughput expression screening platform to optimize the production of antimicrobial peptides

BACKGROUND: Antimicrobial peptides (AMPs) are promising candidates for the development of novel antibiotics, but it is difficult to produce sufficient quantities for preclinical and clinical studies due to their toxicity towards microbial expression hosts. To avoid laborious trial-and-error testing...

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Detalles Bibliográficos
Autores principales: Schreiber, Christine, Müller, Hagen, Birrenbach, Oliver, Klein, Moritz, Heerd, Doreen, Weidner, Tobias, Salzig, Denise, Czermak, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307881/
https://www.ncbi.nlm.nih.gov/pubmed/28193216
http://dx.doi.org/10.1186/s12934-017-0637-5

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