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pH-sensitive micelles for the intracellular co-delivery of curcumin and Pluronic L61 unimers for synergistic reversal effect of multidrug resistance
Pluronic L61 unimers, which are biomacromolecular modulators, and curcumin, a small-molecule modulator, were co-formulated into pH-sensitive micelles to reveal the full synergistic potential of combination drug treatments to reverse multidrug resistance (MDR). Compared to monotherapy, combined thera...
Autores principales: | Hong, Wei, Shi, Hong, Qiao, Mingxi, Zhang, Zehui, Yang, Wenting, Dong, Lingying, Xie, Fucheng, Zhao, Chunpeng, Kang, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307950/ https://www.ncbi.nlm.nih.gov/pubmed/28195164 http://dx.doi.org/10.1038/srep42465 |
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