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Handling and Pathology Reporting of Gastrointestinal Endoscopic Mucosal Resection

Endoscopic mucosal resection (EMR) is a non-invasive alternative to surgery that is now frequently used for resection of early lesions in both upper and lower parts of the gastrointestinal (GI) tract. One of the main advantages of these techniques is providing tissue for histopathological examinatio...

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Autores principales: Geramizadeh, Bita, Owen, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Association of Gastroerterology and Hepatology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308135/
https://www.ncbi.nlm.nih.gov/pubmed/28316760
http://dx.doi.org/10.15171/mejdd.2016.45
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author Geramizadeh, Bita
Owen, David A.
author_facet Geramizadeh, Bita
Owen, David A.
author_sort Geramizadeh, Bita
collection PubMed
description Endoscopic mucosal resection (EMR) is a non-invasive alternative to surgery that is now frequently used for resection of early lesions in both upper and lower parts of the gastrointestinal (GI) tract. One of the main advantages of these techniques is providing tissue for histopathological examination. Pathological examination of endoscopically resected specimens of GI tract is a crucial component of these procedures and is useful for prediction of both the risk of metastasis and lymph node involvement. As the first step, it is very important for the pathologist to handle the EMR gross specimen in the correct way: it should be oriented, and then the margins should be labeled and inked accurately before fixation. In the second step, the EMR pathological report should include all the detailed information about the diagnosis, grading, depth of invasion (mucosa only or submucosal involvement), status of the margins, and the presence or absence of lymphovascular invasion. The current literature (PubMed and Google Scholar) was searched for the words "endoscopic mucosal resection" to find all relevant publications about this technique with emphasis on the pathologist responsibilities.
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spelling pubmed-53081352017-03-17 Handling and Pathology Reporting of Gastrointestinal Endoscopic Mucosal Resection Geramizadeh, Bita Owen, David A. Middle East J Dig Dis Review Article Endoscopic mucosal resection (EMR) is a non-invasive alternative to surgery that is now frequently used for resection of early lesions in both upper and lower parts of the gastrointestinal (GI) tract. One of the main advantages of these techniques is providing tissue for histopathological examination. Pathological examination of endoscopically resected specimens of GI tract is a crucial component of these procedures and is useful for prediction of both the risk of metastasis and lymph node involvement. As the first step, it is very important for the pathologist to handle the EMR gross specimen in the correct way: it should be oriented, and then the margins should be labeled and inked accurately before fixation. In the second step, the EMR pathological report should include all the detailed information about the diagnosis, grading, depth of invasion (mucosa only or submucosal involvement), status of the margins, and the presence or absence of lymphovascular invasion. The current literature (PubMed and Google Scholar) was searched for the words "endoscopic mucosal resection" to find all relevant publications about this technique with emphasis on the pathologist responsibilities. Iranian Association of Gastroerterology and Hepatology 2017-01 /pmc/articles/PMC5308135/ /pubmed/28316760 http://dx.doi.org/10.15171/mejdd.2016.45 Text en © 2017 by Middle East Journal of Digestive Diseases This work is published by Middle East Journal of Digestive Diseases as an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-sa/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited.
spellingShingle Review Article
Geramizadeh, Bita
Owen, David A.
Handling and Pathology Reporting of Gastrointestinal Endoscopic Mucosal Resection
title Handling and Pathology Reporting of Gastrointestinal Endoscopic Mucosal Resection
title_full Handling and Pathology Reporting of Gastrointestinal Endoscopic Mucosal Resection
title_fullStr Handling and Pathology Reporting of Gastrointestinal Endoscopic Mucosal Resection
title_full_unstemmed Handling and Pathology Reporting of Gastrointestinal Endoscopic Mucosal Resection
title_short Handling and Pathology Reporting of Gastrointestinal Endoscopic Mucosal Resection
title_sort handling and pathology reporting of gastrointestinal endoscopic mucosal resection
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308135/
https://www.ncbi.nlm.nih.gov/pubmed/28316760
http://dx.doi.org/10.15171/mejdd.2016.45
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