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Understanding the Snake Venom Metalloproteinases: An Interview with Jay Fox and José María Gutiérrez

Jay W. Fox and José María Gutiérrez recently finished editing a Special Issue on the topic “Snake Venom Metalloproteinases” in Toxins. The Special Issue covers a wide range of topics, including the molecular evolution and structure of snake venom metalloproteinases (SVMPs), the mechanisms involved i...

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Detalles Bibliográficos
Autores principales: Fox, Jay W., Gutiérrez, José María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308265/
https://www.ncbi.nlm.nih.gov/pubmed/28275208
http://dx.doi.org/10.3390/toxins9010033
Descripción
Sumario:Jay W. Fox and José María Gutiérrez recently finished editing a Special Issue on the topic “Snake Venom Metalloproteinases” in Toxins. The Special Issue covers a wide range of topics, including the molecular evolution and structure of snake venom metalloproteinases (SVMPs), the mechanisms involved in the generation of diversity of SVMPs, the mechanism of action of SVMPs, and their role in the pathophysiology of envenomings, with implications for improving the therapy of envenomings. In this interview, we discussed with Jay W. Fox and José María Gutiérrez their research on the SVMPs and their perspectives on the future trends and challenges for studying snake venoms.