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USP21 promotes cell proliferation and metastasis through suppressing EZH2 ubiquitination in bladder carcinoma

Bladder cancer (BC) is the second most common malignant tumor of the urinary tract in the world. In this study, we found that ubiquitin-specific protease (USP21) was upregulated in BC and the ectopic expression of USP21 was closely associated with tumor size and metastasis. Moreover, patients with h...

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Detalles Bibliográficos
Autores principales: Chen, Yong, Zhou, Bo, Chen, Daihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308592/
https://www.ncbi.nlm.nih.gov/pubmed/28223825
http://dx.doi.org/10.2147/OTT.S124795