PPARγ agonists promote differentiation of cancer stem cells by restraining YAP transcriptional activity

Osteosarcoma (OS) is a highly aggressive pediatric bone cancer in which most tumor cells remain immature and fail to differentiate into bone-forming osteoblasts. However, OS cells readily respond to adipogenic stimuli suggesting they retain mesenchymal stem cell-like properties. Here we demonstrate...

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Detalles Bibliográficos
Autores principales: Basu-Roy, Upal, Han, Eugenia, Rattanakorn, Kirk, Gadi, Abhilash, Verma, Narendra, Maurizi, Giulia, Gunaratne, Preethi H., Coarfa, Cristian, Kennedy, Oran D., Garabedian, Michael J., Basilico, Claudio, Mansukhani, Alka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308629/
https://www.ncbi.nlm.nih.gov/pubmed/27528232
http://dx.doi.org/10.18632/oncotarget.11273

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