Exogenous IL-33 overcomes T cell tolerance in murine acute myeloid leukemia

Emerging studies suggest that dominant peripheral tolerance is a major mechanism of immune escape in disseminated leukemia. Using an established murine acute myeloid leukemia (AML) model, we here show that systemic administration of recombinant IL-33 dramatically inhibits the leukemia growth and pro...

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Detalles Bibliográficos
Autores principales: Qin, Lei, Dominguez, Donye, Chen, Siqi, Fan, Jie, Long, Alan, Zhang, Minghui, Fang, Deyu, Zhang, Yi, Kuzel, Timothy M., Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308636/
https://www.ncbi.nlm.nih.gov/pubmed/27517629
http://dx.doi.org/10.18632/oncotarget.11179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308636/
https://www.ncbi.nlm.nih.gov/pubmed/27517629
http://dx.doi.org/10.18632/oncotarget.11179

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