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Exogenous IL-33 overcomes T cell tolerance in murine acute myeloid leukemia
Emerging studies suggest that dominant peripheral tolerance is a major mechanism of immune escape in disseminated leukemia. Using an established murine acute myeloid leukemia (AML) model, we here show that systemic administration of recombinant IL-33 dramatically inhibits the leukemia growth and pro...
Autores principales: | Qin, Lei, Dominguez, Donye, Chen, Siqi, Fan, Jie, Long, Alan, Zhang, Minghui, Fang, Deyu, Zhang, Yi, Kuzel, Timothy M., Zhang, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308636/ https://www.ncbi.nlm.nih.gov/pubmed/27517629 http://dx.doi.org/10.18632/oncotarget.11179 |
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