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The histone methyltransferase G9a as a therapeutic target to override gemcitabine resistance in pancreatic cancer

Gemcitabine (GEM) resistance is a critical issue for pancreatic cancer treatment. The involvement of epigenetic modification in GEM resistance is still unclear. We established a GEM-resistant subline PANC-1-R from the parental PANC-1 pancreatic cancer cells and found the elevation of various chromat...

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Detalles Bibliográficos
Autores principales:	Pan, Mei-Ren, Hsu, Ming-Chuan, Luo, Chi-Wen, Chen, Li-Tzong, Shan, Yan-Shen, Hung, Wen-Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308641/ https://www.ncbi.nlm.nih.gov/pubmed/27531902 http://dx.doi.org/10.18632/oncotarget.11256

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