Dynamics of PBMC gene expression in hepatitis C virus genotype 1-infected patients during combined peginterferon/ribavirin therapy

Hepatitis C virus (HCV) can replicate in peripheral blood mononuclear cells (PBMCs), which can produce interferon to defend against virus infection. We hypothesized that dynamic gene expression in PBMCs might impact the treatment efficacy of peginterferon/ribavirin in HCV patients. PBMCs were collec...

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Detalles Bibliográficos
Autores principales: Lu, Ming-Ying, Huang, Ching-I, Hsieh, Ming-Yen, Hsieh, Tusty-Juan, Hsi, Edward, Tsai, Pei-Chien, Tsai, Yi-Shan, Lin, Ching-Chih, Hsieh, Meng-Hsuan, Liang, Po-Cheng, Lin, Yi-Hung, Hou, Nai-Jen, Yeh, Ming-Lun, Huang, Chung-Feng, Lin, Zu-Yau, Chen, Shinn-Cherng, Huang, Jee-Fu, Chuang, Wan-Long, Dai, Chia-Yen, Yu, Ming-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308654/
https://www.ncbi.nlm.nih.gov/pubmed/27542257
http://dx.doi.org/10.18632/oncotarget.11348

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