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Sulforaphane-induced apoptosis involves the type 1 IP(3) receptor
In this study we show that anti-tumor effect of sulforaphane (SFN) is partially realized through the type 1 inositol 1,4,5-trisphosphate receptor (IP(3)R1). This effect was verified in vitro on three different stable cell lines and also in vivo on the model of nude mice with developed tumors. Early...
Autores principales: | Hudecova, Sona, Markova, Jana, Simko, Veronika, Csaderova, Lucia, Stracina, Tibor, Sirova, Marta, Fojtu, Michaela, Svastova, Eliska, Gronesova, Paulina, Pastorek, Michal, Novakova, Marie, Cholujova, Dana, Kopacek, Juraj, Pastorekova, Silvia, Sedlak, Jan, Krizanova, Olga |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308660/ https://www.ncbi.nlm.nih.gov/pubmed/27528021 http://dx.doi.org/10.18632/oncotarget.8968 |
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