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Therapeutic relevance of the protein phosphatase 2A in cancer
Chromosomal Instability (CIN) is regarded as a unifying feature of heterogeneous tumor populations, driving intratumoral heterogeneity. Polo-Like Kinase 1 (PLK1), a serine-threonine kinase that is often overexpressed across multiple tumor types, is one of the key regulators of CIN and is considered...
Autores principales: | Cunningham, Chelsea E., Li, Shuangshuang, Vizeacoumar, Frederick S., Bhanumathy, Kalpana Kalyanasundaram, Lee, Joo Sang, Parameswaran, Sreejit, Furber, Levi, Abuhussein, Omar, Paul, James M., McDonald, Megan, Templeton, Shaina D., Shukla, Hersh, El Zawily, Amr M., Boyd, Frederick, Alli, Nezeka, Mousseau, Darrell D., Geyer, Ron, Bonham, Keith, Anderson, Deborah H., Yan, Jiong, Yu-Lee, Li-Yuan, Weaver, Beth A., Uppalapati, Maruti, Ruppin, Eytan, Sablina, Anna, Freywald, Andrew, Vizeacoumar, Franco J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308671/ https://www.ncbi.nlm.nih.gov/pubmed/27557495 http://dx.doi.org/10.18632/oncotarget.11399 |
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