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Neferine inhibits proliferation and collagen synthesis induced by high glucose in cardiac fibroblasts and reduces cardiac fibrosis in diabetic mice

Cardiac fibrosis is a common pathological process accompanying diabetes mellitus. In this report, we studied the effects of neferine (a major bisbenzylisoquinline alkaloid derived from lotus embryos) on cardiac fibrosis induced by diabetes mellitus, as well as the underlying molecular pathways. In v...

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Detalles Bibliográficos
Autores principales: Liu, Xue, Song, Xiuhui, Lu, Jianjun, Chen, Xueying, Liang, Ershun, Liu, Xiaoqiong, Zhang, Mingxiang, Zhang, Yun, Du, Zhanhui, Zhao, Yuxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308684/
https://www.ncbi.nlm.nih.gov/pubmed/27533252
http://dx.doi.org/10.18632/oncotarget.11225

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