Mutational profiling of non-small-cell lung cancer patients resistant to first-generation EGFR tyrosine kinase inhibitors using next generation sequencing

Patients with advanced non-small-cell lung cancer (NSCLC) harboring sensitive epithelial growth factor receptor (EGFR) mutations invariably develop acquired resistance to EGFR tyrosine kinase inhibitors (TKIs). Identification of actionable genetic alterations conferring drug-resistance can be helpfu...

Descripción completa

Detalles Bibliográficos
Autores principales: Jin, Ying, Shao, Yang, Shi, Xun, Lou, Guangyuan, Zhang, Yiping, Wu, Xue, Tong, Xiaoling, Yu, Xinmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308688/
https://www.ncbi.nlm.nih.gov/pubmed/27528220
http://dx.doi.org/10.18632/oncotarget.11237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308688/
https://www.ncbi.nlm.nih.gov/pubmed/27528220
http://dx.doi.org/10.18632/oncotarget.11237

Ejemplares similares