Candidate germline polymorphisms of genes belonging to the pathways of four drugs used in osteosarcoma standard chemotherapy associated with risk, survival and toxicity in non-metastatic high-grade osteosarcoma

This study aimed to identify associations between germline polymorphisms and risk of high-grade osteosarcoma (HGOS) development, event-free survival (EFS) and toxicity in HGOS patients treated with neo-adjuvant chemotherapy and surgery. Germline polymorphisms of 31 genes known to be relevant for tra...

Descripción completa

Detalles Bibliográficos
Autores principales: Hattinger, Claudia M., Biason, Paola, Iacoboni, Erika, Gagno, Sara, Fanelli, Marilù, Tavanti, Elisa, Vella, Serena, Ferrari, Stefano, Roli, Andrea, Roncato, Rossana, Giodini, Luciana, Scotlandi, Katia, Picci, Piero, Toffoli, Giuseppe, Serra, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308704/
https://www.ncbi.nlm.nih.gov/pubmed/27566557
http://dx.doi.org/10.18632/oncotarget.11486

Ejemplares similares

Ejemplares similares