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Diacetoxyscirpenol as a new anticancer agent to target hypoxia-inducible factor 1
Hypoxia activates hypoxia-inducible factor 1, which promotes the progression of malignancy by stimulating angiogenesis and by augmenting the ability of tumors to survive. Thus, HIF-1 is one of the most compelling targets for treating cancers. The aim of this study was to find a small molecule that i...
Autores principales: | Choi, Yong-Joon, Shin, Hyun-Woo, Chun, Yang-Sook, Leutou, Alain Simplice, Son, Byeng Wha, Park, Jong-Wan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308714/ https://www.ncbi.nlm.nih.gov/pubmed/27613833 http://dx.doi.org/10.18632/oncotarget.11529 |
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