Cargando…

A single nucleotide polymorphism in the 3′-UTR of STAT3 regulates its expression and reduces risk of pancreatic cancer in a Chinese population

Pancreatic cancer (PC) is one of the deadliest solid malignancies carrying a gloomy 5-year survival rate less than 5%. The signal transducer and activator of transcription 3 (STAT3) is a common transcriptional regulator, whose aberrant expression has been widely found in human cancers, including PC....

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Beibei, Zhu, Ying, Lou, Jiao, Ke, Juntao, Zhang, Yi, Li, Jiaoyuan, Gong, Yajie, Yang, Yang, Tian, Jianbo, Peng, Xiating, Zou, Danyi, Zhong, Rong, Gong, Jing, Chang, Jiang, Li, Lu, Miao, Xiaoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308728/ https://www.ncbi.nlm.nih.gov/pubmed/27577070 http://dx.doi.org/10.18632/oncotarget.11607

Ejemplares similares

A functional variant in GREM1 confers risk for colorectal cancer by disrupting a hsa-miR-185-3p binding site
por: Li, Jiaoyuan, et al.
Publicado: (2017)

BRCA1 missense polymorphisms are associated with poor prognosis of pancreatic cancer patients in a Chinese population
por: Zhu, Ying, et al.
Publicado: (2017)

A functional variant rs4442975 modulating FOXA1-binding affinity does not influence the risk or progression of breast cancer in Chinese Han population
por: Zhang, Yi, et al.
Publicado: (2016)

AWESOME: a database of SNPs that affect protein post-translational modifications
por: Yang, Yang, et al.
Publicado: (2019)

Exome-wide analysis identifies three low-frequency missense variants associated with pancreatic cancer risk in Chinese populations
por: Chang, Jiang, et al.
Publicado: (2018)

Evaluation of polymorphisms in microRNA‐binding sites and pancreatic cancer risk in Chinese population
por: Ke, Juntao, et al.
Publicado: (2019)

Identification of a functional variant for colorectal cancer risk mapping to chromosome 5q31.1
por: Ke, Juntao, et al.
Publicado: (2016)

CancerSplicingQTL: a database for genome-wide identification of splicing QTLs in human cancer
por: Tian, Jianbo, et al.
Publicado: (2019)

Identification of a Potential Regulatory Variant for Colorectal Cancer Risk Mapping to 3p21.31 in Chinese Population
por: Ke, Juntao, et al.
Publicado: (2016)

MAD1L1 Arg558His and MAD2L1 Leu84Met interaction with smoking increase the risk of colorectal cancer
por: Zhong, Rong, et al.
Publicado: (2015)

Identification of a Potential Regulatory Variant for Colorectal Cancer Risk Mapping to Chromosome 5q31.1: A Post-GWAS Study
por: Ke, Juntao, et al.
Publicado: (2015)

Dietary Mushroom Intake May Reduce the Risk of Breast Cancer: Evidence from a Meta-Analysis of Observational Studies
por: Li, Jiaoyuan, et al.
Publicado: (2014)

Educational and Behavioral Counseling in a Methadone Maintenance Treatment Program in China: A Randomized Controlled Trial
por: Liu, Pulin, et al.
Publicado: (2018)

A genetic variant in PIK3R1 is associated with pancreatic cancer survival in the Chinese population
por: Zhu, Ying, et al.
Publicado: (2019)

A Functional p53 Responsive Polymorphism in KITLG, rs4590952, Does not Affect the Risk of Breast Cancer
por: Chen, Wei, et al.
Publicado: (2014)

A Phosphorylation-Related Variant ADD1-rs4963 Modifies the Risk of Colorectal Cancer
por: Shen, Na, et al.
Publicado: (2015)

KRAS and VEGF gene 3'-UTR single nucleotide polymorphisms predicted susceptibility in colorectal cancer
por: Yang, Minnan, et al.
Publicado: (2017)

Association between bilirubin and risk of Non-Alcoholic Fatty Liver Disease based on a prospective cohort study
por: Tian, Jianbo, et al.
Publicado: (2016)

ABTB2 Regulatory Variant as Predictor of Epirubicin-Based Neoadjuvant Chemotherapy in Luminal A Breast Cancer
por: Gong, Yajie, et al.
Publicado: (2020)

The Associations between RNA Splicing Complex Gene SF3A1 Polymorphisms and Colorectal Cancer Risk in a Chinese Population
por: Chen, Xiaohua, et al.
Publicado: (2015)

Regulatory variation within 3’UTR of STAT5A correlates with sudden cardiac death in Chinese populations
por: Yu, Huan, et al.
Publicado: (2021)

Parity and pancreatic cancer risk: evidence from a meta-analysis of twenty epidemiologic studies
por: Zhu, Beibei, et al.
Publicado: (2014)

Relationship between single nucleotide polymorphisms in the 3′UTR of amyloid precursor protein and risk of Alzheimer’s disease and its mechanism
por: Zhou, Qiong, et al.
Publicado: (2019)

Targeting STAT3 in Cancer with Nucleotide Therapeutics
por: K. Lau, Yue-Ting, et al.
Publicado: (2019)

A single-nucleotide polymorphism in the 3′-UTR region of the adipocyte fatty acid binding protein 4 gene is associated with prognosis of triple-negative breast cancer
por: Wang, Wenmiao, et al.
Publicado: (2016)

Streamlining differential exon and 3′ UTR usage with diffUTR
por: Gerber, Stefan, et al.
Publicado: (2021)

TC3A: The Cancer 3′ UTR Atlas
por: Feng, Xin, et al.
Publicado: (2018)

Association between a Single Nucleotide Polymorphism in the 3′-UTR of ARHGEF18 and the Risk of Nonidiopathic Pulmonary Arterial Hypertension in Chinese Population
por: Li, Ding, et al.
Publicado: (2018)

The effect of SOX4 gene 3′UTR polymorphisms on osteoporosis
por: Li, Guo, et al.
Publicado: (2021)

Association of single nucleotide polymorphisms in the 3′UTR region of TPM1 gene with dilated cardiomyopathy: A case-control study
por: Yao, Qiang, et al.
Publicado: (2019)

Systematic analysis on expression quantitative trait loci identifies a novel regulatory variant in ring finger and WD repeat domain 3 associated with prognosis of pancreatic cancer
por: Zhu, Ying, et al.
Publicado: (2022)

Frequency of HLA‑G UTR‑1/UTR‑3/UTR‑7 in women with unexplained recurrent spontaneous abortion
por: Bai, Wei, et al.
Publicado: (2022)

A miRNA Binding Site Single-Nucleotide Polymorphism in the 3′-UTR Region of the IL23R Gene Is Associated with Breast Cancer
por: Wang, Lihong, et al.
Publicado: (2012)

Genome‐Wide 3′‐UTR Single Nucleotide Polymorphism Association Study Identifies Significant Prostate Cancer Risk‐Associated Functional Loci at 8p21.2 in Chinese Population
por: Zhang, Ning, et al.
Publicado: (2022)

A Genetic Variant rs1801274 in FCGR2A as a Potential Risk Marker for Kawasaki Disease: A Case-Control Study and Meta-Analysis
por: Duan, Jiayu, et al.
Publicado: (2014)

peaks2utr: a robust Python tool for the annotation of 3′ UTRs
por: Haese-Hill, William, et al.
Publicado: (2023)

3’UTR polymorphisms in NRAMP1 are associated with the susceptibility to pulmonary tuberculosis: A MOOSE-compliant meta-analysis
por: Liu, Yang, et al.
Publicado: (2019)

Association between 5’-UTR and 3’-UTR Polymorphisms of the TYMS Gene and Breast Cancer in Kurdish Women of Iraq
por: Mohamad, Kazhal Shekh
Publicado: (2021)

Association of single nucleotide polymorphisms in the RAB5B gene 3′UTR region with polycystic ovary syndrome in Chinese Han women
por: Yu, Jia, et al.
Publicado: (2019)

Evolution of 3'UTR-associated RNAs
por: Engelhardt, Jan, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_iu87ja3i1aunv77rsjet01jk6i