Suppression of PC-1/PrLZ sensitizes prostate cancer cells to ionizing radiation by attenuating DNA damage repair and inducing autophagic cell death

Radiotherapy is promising and effective for treating prostate cancer but the addition of a tumor cell radiosensitizer would improve therapeutic outcomes. PC-1/PrLZ, a TPD52 protein family member is frequently upregulated in advanced prostate cancer cells and may be a biomarker of aggressive prostate...

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Detalles Bibliográficos
Autores principales: Shang, Zeng-Fu, Wei, Qiang, Yu, Lan, Huang, Fang, Xiao, Bei-Bei, Wang, Hongtao, Song, Man, Wang, Li, Zhou, Jianguang, Wang, Jian, Li, Shanhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308731/
https://www.ncbi.nlm.nih.gov/pubmed/27694690
http://dx.doi.org/10.18632/oncotarget.11470

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