Evidence from a large-scale meta-analysis indicates eczema reduces the incidence of glioma

We investigated the relationship between eczema and the risk of primary glioma. Relevant studies were selected through electronic searches of PubMed and EMBASE. A meta-analysis of 12 case-control studies and one cohort study was performed. A fixed effect model was applied to analyze 13 studies consi...

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Detalles Bibliográficos
Autores principales: Wang, Guannan, Xu, Suling, Cao, Chao, Dong, Jing, Chu, Yudong, He, Guijuan, Xu, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308749/
https://www.ncbi.nlm.nih.gov/pubmed/27566584
http://dx.doi.org/10.18632/oncotarget.11545
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author Wang, Guannan
Xu, Suling
Cao, Chao
Dong, Jing
Chu, Yudong
He, Guijuan
Xu, Zhiwei
author_facet Wang, Guannan
Xu, Suling
Cao, Chao
Dong, Jing
Chu, Yudong
He, Guijuan
Xu, Zhiwei
author_sort Wang, Guannan
collection PubMed
description We investigated the relationship between eczema and the risk of primary glioma. Relevant studies were selected through electronic searches of PubMed and EMBASE. A meta-analysis of 12 case-control studies and one cohort study was performed. A fixed effect model was applied to analyze 13 studies consisting of 10,897 glioma cases and 56,081 controls. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to assess the strength of the associations. The data demonstrate that eczema significantly reduces the risk of glioma (OR = 0.69, 95% CI = 0.61–0.78, P < 0.001). Additional studies with larger patient cohorts are required to validate our findings.
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spelling pubmed-53087492017-03-09 Evidence from a large-scale meta-analysis indicates eczema reduces the incidence of glioma Wang, Guannan Xu, Suling Cao, Chao Dong, Jing Chu, Yudong He, Guijuan Xu, Zhiwei Oncotarget Research Paper We investigated the relationship between eczema and the risk of primary glioma. Relevant studies were selected through electronic searches of PubMed and EMBASE. A meta-analysis of 12 case-control studies and one cohort study was performed. A fixed effect model was applied to analyze 13 studies consisting of 10,897 glioma cases and 56,081 controls. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to assess the strength of the associations. The data demonstrate that eczema significantly reduces the risk of glioma (OR = 0.69, 95% CI = 0.61–0.78, P < 0.001). Additional studies with larger patient cohorts are required to validate our findings. Impact Journals LLC 2016-08-23 /pmc/articles/PMC5308749/ /pubmed/27566584 http://dx.doi.org/10.18632/oncotarget.11545 Text en Copyright: © 2016 Wang et al. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Paper
Wang, Guannan
Xu, Suling
Cao, Chao
Dong, Jing
Chu, Yudong
He, Guijuan
Xu, Zhiwei
Evidence from a large-scale meta-analysis indicates eczema reduces the incidence of glioma
title Evidence from a large-scale meta-analysis indicates eczema reduces the incidence of glioma
title_full Evidence from a large-scale meta-analysis indicates eczema reduces the incidence of glioma
title_fullStr Evidence from a large-scale meta-analysis indicates eczema reduces the incidence of glioma
title_full_unstemmed Evidence from a large-scale meta-analysis indicates eczema reduces the incidence of glioma
title_short Evidence from a large-scale meta-analysis indicates eczema reduces the incidence of glioma
title_sort evidence from a large-scale meta-analysis indicates eczema reduces the incidence of glioma
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308749/
https://www.ncbi.nlm.nih.gov/pubmed/27566584
http://dx.doi.org/10.18632/oncotarget.11545
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