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Recurrent mutations in NF-κB pathway components, KMT2D, and NOTCH1/2 in ocular adnexal MALT-type marginal zone lymphomas
The pathogenesis of ocular adnexal marginal zone lymphomas of mucosa-associated lymphatic tissue-type (OAML) is still poorly understood. We analyzed 63 cases of such lymphomas for non-synonymous mutations in 24 candidate genes by amplicon sequencing. We validated frequent mutations in the NF-κB regu...
Autores principales: | Johansson, Patricia, Klein-Hitpass, Ludger, Grabellus, Florian, Arnold, Georg, Klapper, Wolfram, Pförtner, Roman, Dührsen, Ulrich, Eckstein, Anja, Dürig, Jan, Küppers, Ralf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308752/ https://www.ncbi.nlm.nih.gov/pubmed/27566587 http://dx.doi.org/10.18632/oncotarget.11548 |
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