Multiple UBXN family members inhibit retrovirus and lentivirus production and canonical NFκΒ signaling by stabilizing IκBα

UBXN proteins likely participate in the global regulation of protein turnover, and we have shown that UBXN1 interferes with RIG-I-like receptor (RLR) signaling by interacting with MAVS and impeding its downstream effector functions. Here we demonstrate that over-expression of multiple UBXN family me...

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Detalles Bibliográficos
Autores principales: Hu, Yani, O’Boyle, Kaitlin, Auer, Jim, Raju, Sagar, You, Fuping, Wang, Penghua, Fikrig, Erol, Sutton, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308826/
https://www.ncbi.nlm.nih.gov/pubmed/28152074
http://dx.doi.org/10.1371/journal.ppat.1006187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308826/
https://www.ncbi.nlm.nih.gov/pubmed/28152074
http://dx.doi.org/10.1371/journal.ppat.1006187

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