Detrimental ELAVL-1/HuR-dependent GSK3β mRNA stabilization impairs resolution in acute respiratory distress syndrome

A hallmark of acute respiratory distress syndrome (ARDS) is accumulation of protein-rich edema in the distal airspaces and its removal is critical for patient survival. Previous studies have shown a detrimental role of Glycogen Synthase Kinase (GSK) 3β during ARDS via inhibition of alveolar epitheli...

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Detalles Bibliográficos
Autores principales: Hoffman, Olivia, Burns, Nana, Vadász, István, Eltzschig, Holger K., Edwards, Michael G., Vohwinkel, Christine U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308835/
https://www.ncbi.nlm.nih.gov/pubmed/28196122
http://dx.doi.org/10.1371/journal.pone.0172116

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