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Proteomics progresses in microbial physiology and clinical antimicrobial therapy
Clinical microbial identification plays an important role in optimizing the management of infectious diseases and provides diagnostic and therapeutic support for clinical management. Microbial proteomic research is aimed at identifying proteins associated with microbial activity, which has facilitat...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309286/ https://www.ncbi.nlm.nih.gov/pubmed/27812806 http://dx.doi.org/10.1007/s10096-016-2816-4 |
| _version_ | 1782507683283206144 |
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| author | Chen, B. Zhang, D. Wang, X. Ma, W. Deng, S. Zhang, P. Zhu, H. Xu, N. Liang, S. |
| author_facet | Chen, B. Zhang, D. Wang, X. Ma, W. Deng, S. Zhang, P. Zhu, H. Xu, N. Liang, S. |
| author_sort | Chen, B. |
| collection | PubMed |
| description | Clinical microbial identification plays an important role in optimizing the management of infectious diseases and provides diagnostic and therapeutic support for clinical management. Microbial proteomic research is aimed at identifying proteins associated with microbial activity, which has facilitated the discovery of microbial physiology changes and host–pathogen interactions during bacterial infection and antimicrobial therapy. Here, we summarize proteomic-driven progresses of host–microbial pathogen interactions at multiple levels, mass spectrometry-based microbial proteome identification for clinical diagnosis, and antimicrobial therapy. Proteomic technique progresses pave new ways towards effective prevention and drug discovery for microbial-induced infectious diseases. |
| format | Online Article Text |
| id | pubmed-5309286 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2016 |
| publisher | Springer Berlin Heidelberg |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-53092862017-02-28 Proteomics progresses in microbial physiology and clinical antimicrobial therapy Chen, B. Zhang, D. Wang, X. Ma, W. Deng, S. Zhang, P. Zhu, H. Xu, N. Liang, S. Eur J Clin Microbiol Infect Dis Review Clinical microbial identification plays an important role in optimizing the management of infectious diseases and provides diagnostic and therapeutic support for clinical management. Microbial proteomic research is aimed at identifying proteins associated with microbial activity, which has facilitated the discovery of microbial physiology changes and host–pathogen interactions during bacterial infection and antimicrobial therapy. Here, we summarize proteomic-driven progresses of host–microbial pathogen interactions at multiple levels, mass spectrometry-based microbial proteome identification for clinical diagnosis, and antimicrobial therapy. Proteomic technique progresses pave new ways towards effective prevention and drug discovery for microbial-induced infectious diseases. Springer Berlin Heidelberg 2016-11-04 2017 /pmc/articles/PMC5309286/ /pubmed/27812806 http://dx.doi.org/10.1007/s10096-016-2816-4 Text en © The Author(s) 2016 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
| spellingShingle | Review Chen, B. Zhang, D. Wang, X. Ma, W. Deng, S. Zhang, P. Zhu, H. Xu, N. Liang, S. Proteomics progresses in microbial physiology and clinical antimicrobial therapy |
| title | Proteomics progresses in microbial physiology and clinical antimicrobial therapy |
| title_full | Proteomics progresses in microbial physiology and clinical antimicrobial therapy |
| title_fullStr | Proteomics progresses in microbial physiology and clinical antimicrobial therapy |
| title_full_unstemmed | Proteomics progresses in microbial physiology and clinical antimicrobial therapy |
| title_short | Proteomics progresses in microbial physiology and clinical antimicrobial therapy |
| title_sort | proteomics progresses in microbial physiology and clinical antimicrobial therapy |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309286/ https://www.ncbi.nlm.nih.gov/pubmed/27812806 http://dx.doi.org/10.1007/s10096-016-2816-4 |
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